[Chronic Hepatitis B (CHB) Supported Studies Committee. Last updated in August 2026]
•   Understanding gaps in the care cascade in CHB, their impact on outcomes, and opportunities to improve.
•   Measuring the impact of a functional cure on the risk of hepatitis B virus (HBV) transmission.
•   Understanding the impact of functional cure in subpopulations in chronic hepatitis B with substantial unmet need (e.g. those at most risk for hepatocellular carcinoma).
•   Optimizing the long-term management and monitoring of patients who have achieved functional cure.
•   Measuring the clinical and patient impacts of reducing quantitative HBsAg levels (certain geographies and/or subpopulations may be prioritized).
•   Advancing and optimizing implementation of CHB functional cure strategies in routine clinical practice (certain geographies and/or subpopulations may be prioritized).